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Home > Health Library > Rotavirus Vaccine: What You Need to Know
Rotavirus is a virus that causes diarrhea, mostly in babies and young children. The diarrhea can be severe and lead to dehydration. Vomiting and fever are also common in babies with rotavirus.
Before rotavirus vaccine, rotavirus disease was a common and serious health problem for children in the United States. Almost all children in the United States had at least one rotavirus infection before their 5th birthday.
Every year before the vaccine was available:
Since the introduction of the rotavirus vaccine, hospitalizations and emergency visits for rotavirus have dropped dramatically.
Two brands of rotavirus vaccine are available. Your baby will get either 2 or 3 doses, depending on which vaccine is used.
Doses are recommended at these ages:
Your child must get the first dose of rotavirus vaccine before 15 weeks of age, and the last by age 8 months. Rotavirus vaccine may safely be given at the same time as other vaccines.
Almost all babies who get rotavirus vaccine will be protected from severe rotavirus diarrhea. And most of these babies will not get rotavirus diarrhea at all.
The vaccine will not prevent diarrhea or vomiting caused by other germs.
Another virus called porcine circovirus (or parts of it) can be found in both rotavirus vaccines. This is not a virus that infects people, and there is no known safety risk. For more information, see http://wayback.archive-it.org/7993/20170406124518/https:/www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm212140.htm
A baby who has had a life-threatening allergic reaction to a dose of rotavirus vaccine should not get another dose. A baby who has a severe allergy to any part of rotavirus vaccine should not get the vaccine. Tell your doctor if your baby has any severe allergies that you know of, including a severe allergy to latex.
Babies with "severe combined immunodeficiency" (SCID) should not get rotavirus vaccine.
Babies who have had a type of bowel blockage called "intussusception" should not get rotavirus vaccine.
Babies who are mildly ill can get the vaccine. Babies who are moderately or severely ill should wait until they recover. This includes babies with moderate or severe diarrhea or vomiting.
Check with your doctor if your baby's immune system is weakened because of:
With a vaccine, like any medicine, there is a chance of side effects. These are usually mild and go away on their own. Serious side effects are also possible but are rare.
Most babies who get rotavirus vaccine do not have any problems with it. But some problems have been associated with rotavirus vaccine:
Mild problems following rotavirus vaccine:
Serious problems following rotavirus vaccine:
There is also a small risk of intussusception from rotavirus vaccination, usually within a week after the 1st or 2nd vaccine dose. This additional risk is estimated to range from about 1 in 20,000 to 1 in 100,000 US infants who get rotavirus vaccine. Your doctor can give you more information.
Problems that could happen after any vaccine:
As with any medicine, there is a very remote chance of a vaccine causing a serious injury or death.
The safety of vaccines is always being monitored. For more information, visit: www.cdc.gov/vaccinesafety.
For intussusception, look for signs of stomach pain along with severe crying. Early on, these episodes could last just a few minutes and come and go several times in an hour. Babies might pull their legs up to their chest.
Your baby might also vomit several times or have blood in the stool, or could appear weak or very irritable. These signs would usually happen during the first week after the 1st or 2nd dose of rotavirus vaccine, but look for them any time after vaccination.
Look for anything else that concerns you, such as signs of a severe allergic reaction, very high fever, or unusual behavior.
Signs of a severe allergic reaction can include hives, swelling of the face and throat, difficulty breathing, or unusual sleepiness. These would usually start a few minutes to a few hours after the vaccination.
If you think it is intussusception, call a doctor right away. If you can't reach your doctor, take your baby to a hospital. Tell them when your baby got the rotavirus vaccine.
If you think it is a severe allergic reaction or other emergency that can't wait, call 9-1-1 or get your baby to the nearest hospital.
Otherwise, call your doctor.
Afterward, the reaction should be reported to the "Vaccine Adverse Event Reporting System" (VAERS). Your doctor might file this report, or you can do it yourself through the VAERS web site at www.vaers.hhs.gov, or by calling 1-800-822-7967.
VAERS does not give medical advice.
The National Vaccine Injury Compensation Program (VICP) is a federal program that was created to compensate people who may have been injured by certain vaccines.
Persons who believe they may have been injured by a vaccine can learn about the program and about filing a claim by calling 1-800-338-2382 or visiting the VICP website at www.hrsa.gov/vaccinecompensation. There is a time limit to file a claim for compensation.
Vaccine Information Statement
42 U.S.C. § 300aa-26
Department of Health and Human Services
Centers for Disease Control and Prevention
Many Vaccine Information Statements are available in Spanish and other languages. See www.immunize.org/vis.
Hojas de Informacián Sobre Vacunas están disponibles en español y en muchos otros idiomas. Visite http://www.immunize.org/vis..
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