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spironolactone

Pronunciation: spir ON oh LAK tone

Brand: Aldactone, CaroSpir

Aldactone

slide 1 of 37, Aldactone,

25 mg, round, yellow, imprinted with ALDACTONE 25, SEARLE 1001

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Aldactone

slide 2 of 37, Aldactone,

100 mg, round, peach, imprinted with SEARLE 1031, ALDACTONE 100

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Aldactone

slide 3 of 37, Aldactone,

50 mg, oval, orange, imprinted with SEARLE 1041, ALDACTONE 50

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Spironolactone

slide 4 of 37, Spironolactone,

50 mg, oval, white, imprinted with R672

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Spironolactone

slide 5 of 37, Spironolactone,

100 mg, round, white, imprinted with R673

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Spironolactone

slide 6 of 37, Spironolactone,

25 mg, round, white, imprinted with R, 803

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Spironolactone

slide 7 of 37, Spironolactone,

50 mg, round, white, imprinted with M 243

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Spironolactone

slide 8 of 37, Spironolactone,

25 mg, round, white, imprinted with M 146

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Spironolactone

slide 9 of 37, Spironolactone,

25 mg, round, white, imprinted with 5880, V

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Spironolactone

slide 10 of 37, Spironolactone,

50 mg, oval, white, imprinted with 58 81, V

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Spironolactone

slide 11 of 37, Spironolactone,

100 mg, round, white, imprinted with 58 82, V

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Spironolactone

slide 12 of 37, Spironolactone,

25 mg, round, white, imprinted with GG 85

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Spironolactone

slide 13 of 37, Spironolactone,

25 mg, round, white, imprinted with R, 803

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Spironolactone

slide 14 of 37, Spironolactone,

25 mg, round, white, imprinted with M 146

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Spironolactone

slide 15 of 37, Spironolactone,

25 mg, round, white, imprinted with MP 35

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Spironolactone

slide 16 of 37, Spironolactone,

50 mg, round, white, imprinted with MP 542

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Spironolactone

slide 17 of 37, Spironolactone,

100 mg, oval, white, imprinted with MP 303

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Spironolactone

slide 18 of 37, Spironolactone,

50 mg, round, yellow, imprinted with AN 514

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Spironolactone

slide 19 of 37, Spironolactone,

100 mg, round, beige, imprinted with AN 515

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Spironolactone

slide 20 of 37, Spironolactone,

50 mg, round, yellow, imprinted with AN 514

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Aldactone

slide 21 of 37, Aldactone,

50 mg, elliptical, peach, imprinted with SEARLE 1041, ALDACTONE 50

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Spironolactone

slide 22 of 37, Spironolactone,

100 mg, round, peach, imprinted with AF

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Spironolactone

slide 23 of 37, Spironolactone,

100 mg, round, brown, imprinted with AN 515

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Spironolactone

slide 24 of 37, Spironolactone,

100 mg, round, peach, imprinted with 5013, G

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Spironolactone

slide 25 of 37, Spironolactone,

100 mg, round, white, imprinted with M 437

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Spironolactone

slide 26 of 37, Spironolactone,

100 mg, round, white, imprinted with LOGO 673

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Spironolactone

slide 27 of 37, Spironolactone,

100 mg, oval, white, imprinted with MP 303

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Spironolactone

slide 28 of 37, Spironolactone,

25 mg, round, yellow, imprinted with AD

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Spironolactone

slide 29 of 37, Spironolactone,

25 mg, round, white, imprinted with AN 511

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Spironolactone

slide 30 of 37, Spironolactone,

25 mg, round, yellow, imprinted with 5011, G

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Spironolactone

slide 31 of 37, Spironolactone,

25 mg, round, white, imprinted with MYLAN 146, 25

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Spironolactone

slide 32 of 37, Spironolactone,

25 mg, round, white, imprinted with MP 35

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Spironolactone

slide 33 of 37, Spironolactone,

50 mg, oval, orange, imprinted with AE

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Spironolactone

slide 34 of 37, Spironolactone,

50 mg, round, yellow, imprinted with AN 514

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Spironolactone

slide 35 of 37, Spironolactone,

50 mg, oval, orange, imprinted with 5012, G

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Spironolactone

slide 36 of 37, Spironolactone,

50 mg, round, white, imprinted with M 243

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Spironolactone

slide 37 of 37, Spironolactone,

50 mg, round, white, imprinted with MP 542

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What is the most important information I should know about spironolactone?

You should not use spironolactone if you Addison's disease, high levels of potassium in your blood, if you are unable to urinate, or if you are also taking eplerenone.

What is spironolactone?

Spironolactone is a potassium-sparing diuretic (water pill) that prevents your body from absorbing too much salt and keeps your potassium levels from getting too low.

Spironolactone is used to treat heart failure, high blood pressure (hypertension), or hypokalemia (low potassium levels in the blood).

Spironolactone also treats fluid retention (edema) in people with congestive heart failure, cirrhosis of the liver, or a kidney disorder called nephrotic syndrome.

Spironolactone is also used to diagnose or treat a condition in which you have too much aldosterone in your body. Aldosterone is a hormone produced by your adrenal glands to help regulate the salt and water balance in your body.

Spironolactone may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking spironolactone?

You should not use spironolactone if you are allergic to it, or if you have:

  • Addison's disease (an adrenal gland disorder);
  • high levels of potassium in your blood (hyperkalemia);
  • if you are unable to urinate; or
  • if you are also taking eplerenone.

Tell your doctor if you have ever had:

  • an electrolyte imbalance (such as low levels of calcium, magnesium, or sodium in your blood);
  • kidney disease;
  • liver disease; or
  • heart disease.

Tell your doctor if you are pregnant or plan to become pregnant. Having congestive heart failure, cirrhosis, or uncontrolled high blood pressure during pregnancy may lead to medical problems in the mother or the baby. Your doctor should decide whether you take spironolactone if you are pregnant.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

How should I take spironolactone?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Do not share this medicine with another person, even if they have the same symptoms you have.

You may take spironolactone with or without food, but take it the same way each time.

You will need frequent medical tests.

This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using spironolactone.

If you need surgery, tell your surgeon you currently use this medicine. You may need to stop for a short time.

If you are being treated for high blood pressure, keep using this medication even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.

Store at room temperature away from heat, light, and moisture.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking spironolactone?

Drinking alcohol can increase certain side effects.

Do not use potassium supplements or salt substitutes, unless your doctor has told you to.

Avoid a diet high in salt. Too much salt will cause your body to retain water and can make this medication less effective.

Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.

What are the possible side effects of spironolactone?

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • a light-headed feeling, like you might pass out;
  • little or no urination;
  • high potassium level --nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement; o
  • signs of other electrolyte imbalances --increased thirst or urination, confusion, vomiting, muscle pain, slurred speech, severe weakness, numbness, loss of coordination, feeling unsteady.

Common side effects may include:

  • breast swelling or tenderness.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect spironolactone?

Using spironolactone with other drugs that make you dizzy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety, depression, or seizures.

Tell your doctor about all your other medicines, especially:

  • colchicine;
  • digoxin;
  • lithium;
  • loperamide;
  • trimethoprim;
  • heart or blood pressure medicine (especially another diuretic);
  • medicine to prevent a blood clot; or
  • NSAIDs (nonsteroidal anti-inflammatory drugs) --aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.

This list is not complete. Other drugs may affect spironolactone, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Where can I get more information?

Your pharmacist can provide more information about spironolactone.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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