Alert

rivastigmine transdermal

Pronunciation: riv a STIG meen

Brand: Exelon

What is the most important information I should know about rivastigmine transdermal?

You should not use this medicine if you have ever had severe redness, itching, or skin irritation where a rivastigmine transdermal skin patch was worn.

What is rivastigmine transdermal?

Rivastigmine transdermal (skin patch) is used to treat mild to moderate dementia caused by Alzheimer's or Parkinson's disease.

Rivastigmine improves the function of nerve cells in the brain. It works by preventing the breakdown of a chemical that is important for the processes of memory, thinking, and reasoning. People with dementia usually have lower levels of this chemical.

Rivastigmine transdermal may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before using rivastigmine transdermal?

You should not use this medicine if you are allergic to rivastigmine or similar medicines, such as felbamate, meprobamate, or carisoprodol.

You should not use this medicine if you have ever had severe redness, itching, or skin irritation where a rivastigmine transdermal skin patch was worn.

Tell your doctor if you have ever had:

  • an ulcer or stomach bleeding;
  • a seizure;
  • heart problems;
  • liver or kidney disease;
  • urination problems; or
  • asthma, chronic obstructive pulmonary disease (COPD), or other breathing disorder.

Tell your doctor if you are pregnant or plan to become pregnant.

It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.

How should I use rivastigmine transdermal?

Do not take rivastigmine capsules or oral liquid at the same time you are wearing the skin patch.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Do not take by mouth. The transdermal patch is for use only on the skin.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

Apply the patch to clean, dry, and hairless skin. Do not use on broken or irritated skin. Press the patch firmly into place for about 30 seconds to make sure it sticks. You may leave the patch on while bathing, showering, or swimming.

Remove the skin patch after 24 hours and replace it with a new one. Always remove an old patch before putting on a new one.

Do not wear more than one rivastigmine patch at a time. Using extra skin patches will not make the medication more effective.

If a patch falls off, apply a new patch and wear it for the rest of the day. Change the patch at your usual time the next day.

Choose a different place on your body to wear the patch each time you put on a new one. Do not use the same skin area twice within 14 days.

Always wash your hands after removing the patch.

After removing a patch, fold it in half so it sticks together and throw it away in a place where children or pets cannot get to it. A used skin patch could be fatal to a child or pet who accidentally chews on the patch. Seek emergency medical attention if this happens.

It may take up to 4 weeks before your symptoms improve. For best results, keep using the patches as directed.

If you need surgery, tell your surgeon you currently use this medicine.

If you stop using rivastigmine for any reason, do not restart the medicine without talking to your doctor first. You may need to start with a lower dose.

Store at room temperature away from moisture and heat. Keep each patch in its foil pouch until you are ready to use it.

What happens if I miss a dose?

If you forget to change the skin patch, remove it and apply a new one as soon as you remember. Do not wear extra patches to make up a missed dose.

Call your doctor for instructions if you miss more than 3 doses of rivastigmine.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using rivastigmine transdermal?

Avoid placing the patch where it will be rubbed by tight clothing.

Avoid touching your eyes after handling a skin patch.

Do not use lotion, oil, or powder on the skin where you plan to apply a skin patch. The patch may not stick to the skin.

Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.

Avoid applying heat to the skin where the patch is worn, because it may increase the amount of medicine your body absorbs. Heat sources include hot tubs, heating pads, heat lamps, saunas, heated water beds, and direct sunlight.

What are the possible side effects of rivastigmine transdermal?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • itching, redness, swelling, peeling, blistering, or skin sores where the patch is worn;
  • severe or ongoing vomiting or diarrhea with weight loss;
  • bloody or tarry stools, cough with bloody mucus or vomit that looks like coffee grounds;
  • a light-headed feeling, like you might pass out;
  • tremors (uncontrolled shaking), restless muscle movements in your eyes, tongue, jaw, or neck;
  • seizures (convulsions);
  • painful or difficult urination;
  • severe skin redness, itching, or irritation; or
  • dehydration symptoms --feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin.

Common side effects may include:

  • headache, dizziness;
  • depression, anxiety;
  • tiredness, muscle weakness;
  • stomach pain; or
  • trouble sleeping.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect rivastigmine transdermal?

Tell your doctor about all your other medicines, especially:

  • medicine to treat depression, anxiety, mood disorders, or mental illness;
  • cold or allergy medicine (Benadryl and others);
  • medicine to treat Parkinson's disease;
  • medicine to treat stomach problems, motion sickness, or irritable bowel syndrome;
  • medicine to treat overactive bladder;
  • bronchodilator asthma medication; or
  • an NSAID (nonsteroidal anti-inflammatory drug such as aspirin, ibuprofen, naproxen, Advil, Motrin, Aleve, and others.

This list is not complete and many other drugs may affect rivastigmine. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Where can I get more information?

Your pharmacist can provide more information about rivastigmine transdermal.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2019 Cerner Multum, Inc. Version: 4.02. Revision date: 3/15/2019.

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