Alert

Updates


COVID-19:
Vaccine information, visitor restrictions, and additional resources | Medicaid: The program is changing and you must take steps to keep your UNC Health providers

silodosin

Pronunciation: SIL oh DOE sin

Brand: Rapaflo

Rapaflo

slide 1 of 2, Rapaflo,

4 mg, capsule, white, imprinted with WATSON 151, 4 mg

Image of Rapaflo
slide 1 of 2
    

Rapaflo

slide 2 of 2, Rapaflo,

8 mg, capsule, white, imprinted with WATSON 152, 8 mg

Image of Rapaflo
slide 2 of 2
    

What is the most important information I should know about silodosin?

Tell your doctor about all your other medicines. Some drugs should not be used with silodosin.

What is silodosin?

Silodosin is an alpha-blocker that is used to improve urination in men with benign prostatic hyperplasia (enlarged prostate).

Silodosin may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking silodosin?

You should not take silodosin if you are allergic to it, or if you have:

  • severe liver disease; or
  • severe kidney disease.

Some drugs should not be used with silodosin. Your treatment plan may change if you also use:

  • nefazodone;
  • an antibiotic --clarithromycin, telithromycin;
  • antifungal medicine --itraconazole, ketoconazole, posaconazole, voriconazole; or
  • antiviral medicine for HIV or hepatitis C --boceprevir, cobicistat, dasabuvir, elvitegravir, indinavir, lopinavir/ritonavir, nelfinavir, ombitasvir, paritaprevir saquinavir, telaprevir, or tipranavir.

Tell your doctor if you have ever had:

  • low blood pressure;
  • kidney disease (or if you are on dialysis);
  • heart disease;
  • prostate cancer;
  • a condition for which you take a diuretic or "water pill"; or
  • if you are on a low-salt diet.

Silodosin can affect your pupils. If you need eye surgery, tell the surgeon about your use of this medicine, even if you no longer take it.

Silodosin is not for use in women, and the effects of this medicine during pregnancy or in breastfeeding women are unknown.

Not approved for use by anyone younger than 18 years old.

How should I take silodosin?

Your doctor may test your prostate specific antigen (PSA) to check for prostate cancer before you take silodosin.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Take once daily with a meal.

If you cannot swallow a capsule whole, open it and mix the medicine with applesauce. Swallow the mixture right away without chewing.

Your blood pressure may get too low during prolonged illness. Call your doctor if you are sick with vomiting or diarrhea.

Your blood pressure will need to be checked often.

Store at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking silodosin?

Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.

What are the possible side effects of silodosin?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have severe dizziness, or if you feel like you might pass out.

Silodosin may cause dizziness or fainting, especially when you first start taking it. You may feel very dizzy when you first wake up or get up too fast from a sitting or lying position.

Common side effects may include:

  • dizziness, feeling like you might pass out;
  • headache;
  • diarrhea;
  • abnormal ejaculation; or
  • stuffy nose, sinus pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect silodosin?

Tell your doctor about all your current medicines. Many drugs can increase your risk of very low blood pressure while taking silodosin, especially:

  • medicines similar to silodosin (alfuzosin, doxazosin, prazosin, tamsulosin, or terazosin);
  • heart or blood pressure medication; or
  • sildenafil (Viagra) and other erectile dysfunction medicines.

This list is not complete and many other drugs may affect silodosin. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Where can I get more information?

Your pharmacist can provide more information about silodosin.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2021 Cerner Multum, Inc. Version: 5.01. Revision date: 6/11/2021.

Your use of the content provided in this service indicates that you have read, understood and agree to the End-User License Agreement, which can be accessed by End-User License Agreement, which can be accessed by clicking on this link.

Related Locations