First Time User? Sign Up Now
First Time User? Enroll now.
Home > Health Library > Hemophilia
Hemophilia is a rare genetic bleeding disorder in which a person inherits problems with certain blood clotting factors, making them unable to work properly. Blood-clotting factors are needed to help stop bleeding after a cut or injury and to prevent spontaneous bleeding.
The hemophilia gene can contain many different errors, leading to different degrees of abnormality in the amount of clotting factor produced. People who have hemophilia are at risk of abnormal bleeding throughout the body, especially in the joints and muscles, which may lead to disabling joint problems.
Hemophilia occurs almost exclusively in men. The disease can be passed from a mother who is a carrier of the genetic defect (but who does not have the disease) to her son. Rarely, a girl can have hemophilia. This occurs only if she inherits a defective gene from both her mother and her father.
Symptoms of hemophilia are usually first noticed during infancy or childhood. However, some people who have milder forms of hemophilia may not develop symptoms until later in life.
The following are signs of hemophilia that may be noticed shortly after birth:
Other symptoms of hemophilia include easy bruising, frequent nosebleeds, blood in the urine, and bleeding after dental work.
Some people who have hemophilia may need to inject (infuse) themselves with clotting factors to prevent uncontrolled bleeding. They may need to do this either regularly or only before activities or situations (such as surgery) when injury or bleeding may occur.
Current as of:
March 28, 2019
Medical Review:E. Gregory Thompson, MD - Internal Medicine & Adam Husney, MD - Family Medicine & Martin J. Gabica, MD - Family Medicine & Brian Leber, MDCM, FRCPC - Hematology
To learn more about Healthwise, visit Healthwise.org.
© 1995-2019 Healthwise, Incorporated. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.
2615 Lake Drive
Raleigh, NC 27607
901 Ridgefield Drive
Raleigh, NC 27609
4420 Lake Boone Trail
Raleigh, NC 27607
934 Vandora Springs Road
Garner, NC 27529
1505 SW Cary Parkway
Cary, NC 27511
UNC REX Healthcare4420 Lake Boone TrailRaleigh, NC 27607, USA919-784-3100
Chosen for Excellence
Co-Worker & Physician Login
UNC Health Talk
Copyright 2020 UNC Health Care. All rights reserved.